P443 A sprint not a marathon: initial outcomes from a physiotherapist-led specialist cystic fibrosis (CF) Cardio-Pulmonary Exercise Testing (CPET) service for Wales

نویسندگان

چکیده

Measurement of VO2peak by CPET is the gold-standard method to evaluate aerobic fitness. The All Wales Adult CF Centre (AWACFC) established a specific service in 2022. PwCF were offered at clinic appointments. protocol comprised Godfrey cycle ergometer with rest, warm up, test and recovery phases. Pulmonary gas exchange, ventilation heart rate monitored continuously. In total 48 CPETs completed which 89% (n = 42) met criteria set out ERS taskforce algorithm for being maximal effort. Most participants male (70%; n 33), ppFEV1 >80% (61%; 29), on CFTR modulators (96%; 45) no liver disease (74%; 35). Mean length was 9 mins 16 secs. For majority pwCF this their first 46, 96%). patients stopped due leg fatigue (77%, 37), 30% 14) able provide sputum samples post CPET. Test acceptability 4.6/5 (Likert scale). given personalised exercise advice follow up from physiotherapy team. Of effort tests low (<40% predicted) FEV1 had lower VO2 peak mean 21.7 (58% predicted, range 20–23 mL/min/kg) compared those high (>80% who achieved 31.9 (82% 19.1–49.9 mL/min/kg). Acceptability high, most completing Leg reason terminating cases. benefitted post-CPET prescription. Additional collected added microbiological surveillance monitoring post-modulator era.

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ژورنال

عنوان ژورنال: Journal of Cystic Fibrosis

سال: 2023

ISSN: ['1569-1993', '1873-5010']

DOI: https://doi.org/10.1016/s1569-1993(23)00811-1